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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LATS1 All Species: 36.06
Human Site: T845 Identified Species: 56.67
UniProt: O95835 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95835 NP_004681.1 1130 126870 T845 R D G H I K L T D F G L C T G
Chimpanzee Pan troglodytes XP_001173355 1130 126853 T845 R D G H I K L T D F G L C T G
Rhesus Macaque Macaca mulatta XP_001090321 809 89257 I554 D K S M F V K I K T L G I G A
Dog Lupus familis XP_534537 1097 121903 T817 L D G H I K L T D F G L C T G
Cat Felis silvestris
Mouse Mus musculus Q8BYR2 1129 126167 T844 R D G H I K L T D F G L C T G
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506215 1121 123969 T835 R D G H I K L T D F G L C T G
Chicken Gallus gallus XP_419666 1136 127431 T851 R D G H I K L T D F G L C T G
Frog Xenopus laevis NP_001087838 1118 125984 T831 R D G H I K L T D F G L C T G
Zebra Danio Brachydanio rerio NP_001018346 1068 120780 F793 D F G L C T G F R W T H D S K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VA38 1105 122470 I849 R D I K P D N I L I D R D G H
Honey Bee Apis mellifera XP_395146 1137 124999 T881 R D G H I K L T D F G L C T G
Nematode Worm Caenorhab. elegans Q2L6W9 476 55529 R221 D N L L L D A R G H V K L S D
Sea Urchin Strong. purpuratus XP_795100 1199 133231 T921 R D G H I K L T D F G L C T G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53894 756 86927 H501 F G L S T G F H K T H D S N Y
Red Bread Mold Neurospora crassa P38679 598 67999 I343 R D I K P D N I L L D R G G H
Conservation
Percent
Protein Identity: 100 99.6 35.8 50.9 N.A. 92.8 N.A. N.A. 80.8 85.2 74.7 63.1 N.A. 38.6 40.2 20.7 38
Protein Similarity: 100 99.8 44.7 63.4 N.A. 96.7 N.A. N.A. 87.1 92.1 83.4 73.7 N.A. 50.2 52.6 29.6 51.9
P-Site Identity: 100 100 0 93.3 N.A. 100 N.A. N.A. 100 100 100 6.6 N.A. 13.3 100 0 100
P-Site Similarity: 100 100 0 93.3 N.A. 100 N.A. N.A. 100 100 100 20 N.A. 13.3 100 20 100
Percent
Protein Identity: N.A. N.A. N.A. N.A. 28 24.4
Protein Similarity: N.A. N.A. N.A. N.A. 42.3 35.5
P-Site Identity: N.A. N.A. N.A. N.A. 0 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. 0 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 7 % A
% Cys: 0 0 0 0 7 0 0 0 0 0 0 0 60 0 0 % C
% Asp: 20 74 0 0 0 20 0 0 60 0 14 7 14 0 7 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 7 7 0 0 7 0 7 7 0 60 0 0 0 0 0 % F
% Gly: 0 7 67 0 0 7 7 0 7 0 60 7 7 20 60 % G
% His: 0 0 0 60 0 0 0 7 0 7 7 7 0 0 14 % H
% Ile: 0 0 14 0 60 0 0 20 0 7 0 0 7 0 0 % I
% Lys: 0 7 0 14 0 60 7 0 14 0 0 7 0 0 7 % K
% Leu: 7 0 14 14 7 0 60 0 14 7 7 60 7 0 0 % L
% Met: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 0 0 0 0 14 0 0 0 0 0 0 7 0 % N
% Pro: 0 0 0 0 14 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 67 0 0 0 0 0 0 7 7 0 0 14 0 0 0 % R
% Ser: 0 0 7 7 0 0 0 0 0 0 0 0 7 14 0 % S
% Thr: 0 0 0 0 7 7 0 60 0 14 7 0 0 60 0 % T
% Val: 0 0 0 0 0 7 0 0 0 0 7 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _